Unfortunately, the solution stability of this product is not determined.
Fortfahren mit
SML2156
Erlotinib hydrochloride
≥98% (HPLC), EGFR kinase inhibitor, powder
Synonym(e):
774 hydrochloride, CP-358, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride, OSI-744 hydrochloride
Anmelden zur Ansicht der Organisations- und Vertragspreise.
Größe auswählen
Ansicht ändern
| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
50 mg | Warenkorb auf Verfügbarkeit prüfen | € 62,60 |
100 mg | Warenkorb auf Verfügbarkeit prüfen | € 126,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C22H23N3O4 · HCl
CAS-Nummer:
Molekulargewicht:
429.90
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Technischer Dienst
Benötigen Sie Hilfe? Unser Team von erfahrenen Wissenschaftlern ist für Sie da.
Unterstützung erhaltenProduktname
Erlotinib hydrochloride, ≥98% (HPLC)
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
−20°C
SMILES string
Cl.N(c3cc(ccc3)C#C)c1ncnc2c1cc(c(c2)OCCOC)OCCOC
InChI
1S/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25);1H
InChI key
GTTBEUCJPZQMDZ-UHFFFAOYSA-N
General description
Erlotinib hydrochloride is an antineoplastic drug. It regulates mechanistic target of rapamycin (mTOR) inhibition, epidermal growth factor receptor down-regulation and epidermal interstitial transformation (EMT) suppression.
Application
Erlotinib hydrochloride has been used to activate mitochondrial fragmentation in a human PANC-1 pancreatic cancer cell line.
Biochem/physiol Actions
EGFR kinase inhibitor; Antineoplastic
Erlotinib hydrochloride is an inhibitor of the receptor tyrosine kinase EGFR (epidermal growth factor receptor). It is used clinically for the treatment of non-small cell lung cancer (NSCLC) and in combination for metastatic pancreatic cancer.
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) | assay ≥95% (HPLC) |
| form powder | form powder | form powder | form powder |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. room temp | storage temp. room temp |
| storage condition desiccated | storage condition desiccated | storage condition desiccated | storage condition desiccated |
| solubility DMSO: 2 mg/mL, clear (warmed) | solubility H2O: 2 mg/mL, clear (warmed) | solubility DMSO: ≥10 mg/mL | solubility DMSO: 2 mg/mL, clear (warmed) |
| color white to beige | color white to beige | color white to off-white | color white to beige |
Still not finding the right product?
Explore all of our products under Erlotinib hydrochloride
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Hier finden Sie alle aktuellen Versionen:
Besitzen Sie dieses Produkt bereits?
In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
-
How long is your erlotinib hydrochloride stable as aliquots dissolved in DMSO or water at -20 degrees? And how long is it stable when added to cell culture medium at 37 degrees at 5% CO2?
1 answer-
Helpful?
-