SML2054

SEA0400

≥98% (HPLC), Na+−Ca++ exchanger (NCX) inhibitor, powder

• Synonym(e): SEA0400, 2-[4-[(2,5-Difluorophenyl)methoxy]phenoxy]-5-ethoxybenzenamine, SEA 0400
• Empirische Formel (Hill-System): C₂₁H₁₉F₂NO₃
• CAS-Nummer: 223104-29-8
• Molekulargewicht: 371.38
• NACRES: NA.77
• UNSPSC Code: 12352200
• MDL number: MFCD07772188
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: SEA0400, ≥98% (HPLC)
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: CCOC1=CC=C(OC2=CC=C(OCC3=C(F)C=CC(F)=C3)C=C2)C(N)=C1
• InChI: 1S/C21H19F2NO3/c1-2-25-18-8-10-21(20(24)12-18)27-17-6-4-16(5-7-17)26-13-14-11-15(22)3-9-19(14)23/h3-12H,2,13,24H2,1H3
• InChI key: YSUBLPUJDOWYDP-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Potent and selective inhibitor of Na+−Ca++ exchanger (NCX)

SEA0400 is a potent and selective inhibitor of Na⁺/Ca²⁺exchanger (NCX). SEA0400 potently inhibits Na⁺/Ca²⁺ exchanger activity in rat astrocytes, microglia, cultured neurons, and rat cardiomyocytes.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable