SML1871

KIN1400

≥98% (HPLC)

• Synonym(e): 7-[(2-Benzothiazolylamino)[4-(difluoromethoxy)phenyl]methyl]-8-quinolinol
• Empirische Formel (Hill-System): C₂₄H₁₇F₂N₃O₂S
• CAS-Nummer: 446826-86-4
• Molekulargewicht: 449.47
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder
• Quality level: 100

Eigenschaften

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 30 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC(C(N=CC=C1)=C1C=C2)=C2C(C3=CC=C(OC(F)F)C=C3)NC4=NC5=CC=CC=C5S4
• InChI: 1S/C24H17F2N3O2S/c25-23(26)31-16-10-7-15(8-11-16)20(29-24-28-18-5-1-2-6-19(18)32-24)17-12-9-14-4-3-13-27-21(14)22(17)30/h1-13,20,23,30H,(H,28,29)
• InChI key: YDSHHDISKUSKFW-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

KIN1400 is innate immune agonists of IRF3 activation that induces IRF3 and MAVS dependent innate immune antiviral genes and IFNβ expression. KIN1400 is a broad spectrum antiviral compound that suppresses replication of hepatitis C virus, West Nile virus, dengue virus and other Flaviviridae, as well as Filoviridae (EV), Orthomyxoviridae (influenza A virus), Arenaviridae (LV) and Paramyxoviridae (RCV, NV).

KIN1400 is innate immune agonists of IRF3 activation.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3