Direkt zum Inhalt
Merck

Fortfahren mit

SML1317

XAP044

≥98% (HPLC)

Synonym(e):

7-Hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one, XAP 044

Anmelden zur Ansicht der Organisations- und Vertragspreise.

Über diesen Artikel

Empirische Formel (Hill-System):
C15H9IO4
CAS-Nummer:
Molekulargewicht:
380.13
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
protect from light


Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C1C(OC2=CC=C(I)C=C2)=COC3=C1C=CC(O)=C3

InChI

1S/C15H9IO4/c16-9-1-4-11(5-2-9)20-14-8-19-13-7-10(17)3-6-12(13)15(14)18/h1-8,17H

InChI key

XXZKJJYWINSUMJ-UHFFFAOYSA-N

Biochem/physiol Actions

XAP044 is a brain penetrant, potent and selective mGlu7 (metabotropic glutamate receptor subtype 7) antagonist that inhibits lateral amygdala long-term potentiation (LTP) in brain slices from wild type mice. XAP044 binds to a pocket localized in mGlu7′s extracellular Venus flytrap domain (VFTD) close to the binding site of the orthosteric agonist L-glutamate. XAP044 exhibits a wide-spectrum anti-stress, antidepressant- and anxiolytic-like efficacy in rodent behavioral model.
XAP044 is a brain penetrant, potent and selective mGlu7 antagonist.

Other Notes

Light sensitive. This compound has Iodine and should be kept in the dark.

Ähnliche Artikel vergleichen

Vollständigen Vergleich anzeigen

Unterschiede anzeigen

1 of 1

Dieser Artikel
M5820SML0361SML0699
description

≥98% (HPLC)

description

≥98% (HPLC), powder

description

≥98% (HPLC)

description

≥97% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥97% (HPLC)

form

powder

form

powder

form

powder

form

lyophilized powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: 20 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: >15 mg/mL

solubility

DMSO: 5 mg/mL, clear (warmed)

storage condition

protect from light

storage condition

protect from light

storage condition

protect from light

storage condition

protect from light


Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Dokumente section.

Wenn Sie Hilfe benötigen, wenden Sie sich bitte an Kundensupport

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen



Questions

Reviews

No rating value

Active Filters