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SML1220

Doripenem hydrate

≥98% (HPLC), Ultra-broad spectrum carbapenem antibiotic, powder

Synonym(e):

(4R,5S,6S)-3-[[(3S,5S)-5-[[(Aminosulfonyl)amino]methyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid hydrate

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Ihnen/SKUVerfügbarkeitPreis
10 mg
Warenkorb auf Verfügbarkeit prüfen
€ 114,00
50 mg
Warenkorb auf Verfügbarkeit prüfen
€ 445,00
€ 378,25

Über diesen Artikel

Empirische Formel (Hill-System):
C15H24N4O6S2 · H2O
CAS-Nummer:
Molekulargewicht:
438.52
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder

€ 114,00


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Produktname

Doripenem hydrate, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

H2O: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

[S](=O)(=O)(NC[C@H]1NC[C@H](C1)SC2=C(N3[C@H]([C@H]2C)[C@H](C3=O)[C@H](O)C)C(=O)O)N.O

InChI

1S/C15H24N4O6S2.H2O/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25;/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25);1H2/t6-,7-,8+,9+,10-,11-;/m1./s1

InChI key

NTUBEBXBDGKBTJ-WGLOMNHJSA-N

Biochem/physiol Actions

Doripenem is an ultra-broad spectrum carbopenem antibiotic.
Doripenem is an ultra-broad spectrum carbopenem antibiotic. Doripenem is active against both gram-positive and gram-negative bacteria.
Doripenem hydrate is used to treat complicated urinary infection including Pyelonephritis caused by E.coli. Doripenem hydrate is promoted in the United States as DORIBAX®. This drug is synthesized from p-nitrobenzyl-protected enolphosphate 2b and N-(p-nitrobenzyloxycarbonyl)-protected aminomethylpyrrolidine.

Legal Information

DORIBAX is a registered trademark of Shionogi Inc.

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Dieser Artikel
SML1238I0160SML0306
form

powder

form

powder

form

powder

form

powder

assay

≥98% (HPLC)

assay

≥90% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

room temp

storage temp.

−20°C

storage temp.

−20°C

solubility

H2O: 5 mg/mL, clear (warmed)

solubility

-

solubility

-

solubility

H2O: ≥5 mg/mL (warmed)

color

white to beige

color

white to yellow

color

-

color

white to beige


Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

  1. May I enquire on the recommended storage condition of the reconstituted working solution and the estimated shelf life of both the neat and working solution? Is there also a recommended transport temperature for the product?

    1 answer
    1. Unfortunately, the stability of this product upon reconstitution has not been determined. It is recommended to use freshly prepared solutions. This product is shipped at ambient temperature during transport. However, for long-term storage, the powder form is maintained at 2-8°C. Please see the links below to publications reporting the stability of this material in solution:
      https://pubmed.ncbi.nlm.nih.gov/20811032/
      https://pubmed.ncbi.nlm.nih.gov/19108795/

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