SML0484

KS-176

≥98% (HPLC)

• Synonym(e): N-[4-(2-Hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]-benzamide
• Empirische Formel (Hill-System): C₂₂H₁₉N₃O₅
• CAS-Nummer: 1253452-78-6
• Molekulargewicht: 405.40
• NACRES: NA.77
• PubChem Substance ID: 329825435
• UNSPSC Code: 12161501
• MDL number: MFCD22666402
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• InChI: 1S/C22H19N3O5/c26-14-13-15-5-9-17(10-6-15)23-22(28)19-3-1-2-4-20(19)24-21(27)16-7-11-18(12-8-16)25(29)30/h1-12,26H,13-14H2,(H,23,28)(H,24,27)
• SMILES string: OCCc1ccc(NC(=O)c2ccccc2NC(=O)c3ccc(cc3)[N+]([O-])=O)cc1
• InChI key: LTWQQWSXYYXVGA-UHFFFAOYSA-N
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 15 mg/mL (clear solution)
• storage temp.: 2-8°C

Beschreibung

Biochem/physiol Actions

KS-176 is a potent specific inhibitor of Breast Cancer Resistance Protein (BCRP) / ATP-binding cassette sub-family G member 2 (ABCG2) with no inhibition of the ATP binding cassette (ABC) transporters P-gp and MRP1.

KS-176 is a potent specific inhibitor of Breast Cancer Resistance Protein (BCRP) / ATP-binding cassette sub-family G member 2 (ABCG2).

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable