SML0284

Mycophenolat-Mofetil

≥98% (HPLC), Mycophenolic acid prodrug, powder

• Synonym(e): (4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexensäure-2-(4-morpholinyl)-ethylester, RS 61443, TM-MMF
• Empirische Formel (Hill-System): C₂₃H₃₁NO₇
• CAS-Nummer: 128794-94-5
• Molekulargewicht: 433.49
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825292
• NACRES: NA.77
• MDL number: MFCD00867568
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Mycophenolat-Mofetil, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: ≥15 mg/mL
• storage temp.: room temp
• SMILES string: COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(=O)OCCN3CCOCC3
• InChI: 1S/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3/b15-4+
• InChI key: RTGDFNSFWBGLEC-SYZQJQIISA-N
• Gene Information: human ... IMPDH1(3614), IMPDH2(3615)

Beschreibung

Application

Mycophenolate mofetil has been used to treat wild-type embryos for inhibiting nucleotide synthesis.[1]

Biochem/physiol Actions

Mycophenolat-mofetil ist ein Pro-Pharmakon von Mycophenolsäure (Kat.-Nr. M5255), das durch unspezifische Esterase in vivo zur Stammsubstanz gespalten wird. Mycophenolsäure hemmt Inosinmonophosphat-Dehydrogenaseund ist ein wirksames immunsuppressives Mittel.

Mycophenolat-mofetil ist ein Pro-Pharmakon von Mycophenolsäure und ein wirksames immunsuppressives Mittel.

Mycophenolate mofetil functions as a rate-limiting enzyme in de novo synthesis of guanosine nucleotides.

Sicherheitshinweise

• pictograms: GHS08,GHS07,GHS09
• signalword: Danger
• hcodes: H302,H360D,H372,H410
• pcodes: P202 - P260 - P264 - P273 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B - STOT RE 1
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable