SML0133

Nomegestrol-acetat

≥98% (HPLC)

• Synonym(e): 17-Acetoxy-6-methyl-19-norpregna-4,6-dien-3,20-dion, NOMAc, Org 10486-0
• Empirische Formel (Hill-System): C₂₃H₃₀O₄
• CAS-Nummer: 58652-20-3
• Molekulargewicht: 370.48
• UNSPSC Code: 51111800
• PubChem Substance ID: 329825183
• EC Number: 261-379-8
• MDL number: MFCD00941390

Eigenschaften

• assay: ≥98% (HPLC)
• form: powder
• color: white to tan
• solubility: DMSO: ≥7 mg/mL
• storage temp.: 2-8°C
• SMILES string: CC(=O)O[C@@]1(CC[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@@H]4[C@H]3CC[C@]12C)C(C)=O
• InChI: 1S/C23H30O4/c1-13-11-20-18(17-6-5-16(26)12-19(13)17)7-9-22(4)21(20)8-10-23(22,14(2)24)27-15(3)25/h11-12,17-18,20-21H,5-10H2,1-4H3/t17-,18-,20-,21+,22+,23+/m1/s1
• InChI key: IIVBFTNIGYRNQY-YQLZSBIMSA-N

Beschreibung

Biochem/physiol Actions

Nomegestrol acetate (NOMAc) is a potent, highly selective progestogen, a full agonist at the progesterone receptor, with no or minimal binding to other steroid receptors. It shows potent antigonadotropic activity mediated at the hypothalamic and pituitary level with strong antiestrogenic effects and a partial antiandrogenic effect. NOMAc is used in various formulations as a contraceptive.

Progestogen, contraceptive

Sicherheitshinweise

• pictograms: GHS08,GHS09
• signalword: Warning
• hcodes: H361fd,H400
• pcodes: P201 - P273 - P308 + P313
• Hazard Classifications: Aquatic Acute 1 - Repr. 2
• Lagerklasse: 13 - Non Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable