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SCP0170
Granulocyte Elastase Substrate human
≥95% (HPLC), lyophilized
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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
10 mg | Versand in der Regel in 2 Wochen. | € 115,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C21H27N5O6
Molekulargewicht:
445.47
UNSPSC Code:
12352204
NACRES:
NA.32
€ 115,00
Versand in der Regel in 2 Wochen.
Technischer Dienst
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Unterstützung erhaltenProduktname
Granulocyte Elastase Substrate human,
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥85%
storage condition
protect from light
storage temp.
−20°C
General description
Elastase, a glycoprotein, is a member of the serine proteases family. It is synthesized by human polymorphonuclear (PMN) leukocytes or by the pancreas. Human granulocyte elastase is liberated in large amounts from granulocytes in chronic inflammatory joint disorders.[1]
Biochem/physiol Actions
Elastase(s) can be assayed and differentiated using chromogenic and fluorogenic Pro-Val peptide substrates such as Glp-Pro-Val-pNA and MeOSuc-Ala-Ala-Pro-Val-4-MNA.
Elastase is a catalytic enzyme that catalyzes the cleavage of carboxyl groups on tiny hydrophobic amino acids including glycine, alanine, and valine. Its main function is to break down elastin. Free elastase in some purulent synovial fluids plays a key role in articular cartilage breakdown. Increased elastase levels in the plasma have been seen in patients with evident rheumatoid arthritis.[1]
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| description - | description - | description >97% (SDS-PAGE), G-CSF, recombinant, expressed in E. coli, suitable for cell culture | description Elastase, Human Neutrophil, CAS 9004-06-2, is a serine protease that degrades elastin, collagen, and proteoglycans |
| assay ≥95% (HPLC) | assay ≥95% (HPLC) | assay >97% (SDS-PAGE) | assay - |
| form lyophilized | form lyophilized | form lyophilized powder | form lyophilized solid |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| storage condition protect from light | storage condition protect from light | storage condition - | storage condition OK to freeze |
| composition Peptide Content, ≥85% | composition Peptide Content, ≥80% | composition - | composition - |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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