SAB5202074

Monoclonal Anti-beta 4 Spectrin-R-Phycoerythrin antibody produced in mouse

clone S393-2, affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-SPTBN4
• UNSPSC-Code: 12352203
• NACRES: NA.45

Eigenschaften

• Biologische Quelle: mouse
• Konjugat: phycoerythrin (R-PE) conjugate
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: S393-2; monoclonal
• Beschreibung: clone S393-2, purified immunoglobulin, buffered aqueous solution; target molecular weight: 200 kDa
• Form: buffered aqueous solution
• Speziesreaktivität: mouse (Predicted), African green monkey (Tested), rat (Predicted), human (Tested)
• Verpackung: pkg of 100 μg
• Lagerbedingungen: avoid repeated freeze/thaw cycles; protect from light
• Konzentration: 1.0 mg/mL
• Methode(n): immunofluorescence: 1:100; western blot: 1:1000
• Isotyp: IgG1
• UniProt-Hinterlegungsnummer: Q9H254
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... SPTBN4(57731)

Beschreibung

Immunogen

Immunogen Description: Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin

Immunogen Region: C-terminal

Immunogen Species: Human

Immunogen type: Fusion protein

Anwendung

Western blotting
Dilution 1:1000
Tissue/Cell Type Used: monkey COS-Beta-4-Spectrin-His

Immunofluorescence
Dilution 1:100
Tissue/Cell Type Used: SK-N-BE

Physikalische Form

50% glycerol, 0.1% sodium azide

PBS pH 7.4

Angaben zur Herstellung

Derived from animal serum

Lagerung und Haltbarkeit

Protect from light; avoid repeated freeze-thaw cycles. Store at -20 °C long-term, 2-8 °C short-term.

Sonstige Hinweise

Additional Product Details:
Does not cross react with other Beta-spectrins
Lot Expiration/Retest Date: Expires 1 year from purchase

Target/Gene Description: Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart . Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier .
Purification method: Protein G purified
Product type: Primary antibody
Antibody structure: Whole Antibody
Protein ID: NP_066022.2

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable