SAB4702047

Monoclonal Anti-CD81 APC-Cyanine7 produced in mouse

• Synonym(e): CVID6, S5.7, TAPA1, TSPAN28
• UNSPSC-Code: 12352203

Eigenschaften

• Konjugat: APC-Cy7 conjugate
• Qualitätsniveau: 100
• Antikörper-Produkttyp: primary antibodies
• Klon: M38, monoclonal
• Form: buffered aqueous solution
• Speziesreaktivität: ( Human), rabbit, ( Cat)
• Methode(n): flow cytometry: suitable
• Isotyp: IgG1
• UniProt-Hinterlegungsnummer: P60033
• Lagertemp.: 2-8°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CD81(975)

Beschreibung

Allgemeine Beschreibung

CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.

Spezifität

The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Immunogen

MOLT-4 (human T-ALL cell line)

Physikalische Form

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Angaben zur Herstellung

Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Lagerung und Haltbarkeit

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Sonstige Hinweise

The antibody solution should be gently mixed before use.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable