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SAB4700552

Sigma-Aldrich

Monoclonal Anti-Cd3e antibody produced in hamster

clone 145-2C11, purified immunoglobulin, buffered aqueous solution

Synonym(e):

Anti-CD3

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

hamster

Konjugat

unconjugated

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

145-2C11, monoclonal

Form

buffered aqueous solution

Speziesreaktivität

mouse

Konzentration

1 mg/mL

Methode(n)

flow cytometry: suitable

Isotyp

IgG

NCBI-Hinterlegungsnummer

NM_007648.4

UniProt-Hinterlegungsnummer

P22646

Versandbedingung

wet ice

Lagertemp.

2-8°C

Angaben zum Gen

mouse ... Cd3e(12501)

Allgemeine Beschreibung

The hamster monoclonal antibody 145-2C11 reacts with mouse CD3 (epsilon subunit). This antibody is commonly used as a phenotypic marker for mouse T cells.

Immunogen

Mouse BM10-37 cytotoxic T lymphocytes

Anwendung

The reagent is designed for Flow Cytometry analysis using 1-2 μg reagent / 1e6 cells in a suspension.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
520762
522547
516279
B32K

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Die Dokumentenbibliothek aufrufen

Susanne M A Lens et al.
Molecular and cellular biology, 22(15), 5419-5433 (2002-07-09)
The caspase 8 inhibitor c-FLIP(L) can act in vitro as a molecular switch between cell death and growth signals transmitted by the death receptor Fas (CD95). To elucidate its function in vivo, transgenic mice were generated that overexpress c-FLIP(L) in
Lisa A Pitcher et al.
European journal of immunology, 35(12), 3643-3654 (2005-11-01)
T cell receptor (TCR) signal transduction is mediated by the immunoreceptor tyrosine-based activation motifs (ITAM). The ten ITAM in the TCR complex are distributed in two distinct signaling modules termed TCR zetazeta and CD3 gammaepsilon/deltaepsilon. To delineate the specific role
M Hanief Sofi et al.
Molecular immunology, 46(7), 1443-1450 (2009-02-03)
T helper (Th) cell differentiation is a key event to mount an appropriate immune response. Th1 and Th2 cells produce their signature cytokines IFN-gamma and IL-4, respectively. However, as we have reported, CD4 T cells selected by MHC class II-expressing
Marcel Wuthrich et al.
The Journal of experimental medicine, 197(11), 1405-1416 (2003-06-05)
Systemic fungal infections with primary and opportunistic pathogens have become increasingly common and represent a growing health menace in patients with AIDS and other immune deficiencies. T lymphocyte immunity, in particular the CD4+ Th 1 cells, is considered the main
Lingqiao Zhu et al.
Journal of immunology (Baltimore, Md. : 1950), 191(2), 737-744 (2013-06-19)
MHC class II-expressing thymocytes can efficiently mediate positive selection of CD4 T cells in mice. Thymocyte-selected CD4 (T-CD4) T cells have an innate-like phenotype similar to invariant NKT cells. To investigate the development and function of T-CD4 T cells in-depth
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