SAB4502387

Anti-PKG2 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): CGK 2, Type II cGMP-dependent protein kinase, cGKII
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 87 kDa
• Speziesreaktivität: mouse, rat, human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:40000; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: Q13237
• UniProt-Hinterlegungsnummer: Q13237
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... PRKG2(5593)

Beschreibung

Allgemeine Beschreibung

Anti-PKG2 Antibody detects endogenous levels of total PKG2 protein.

Type II cGMP-dependent protein kinase (PRKG2) is encoded by the gene mapped to human chromosome 4q13.1–q21.1.

Immunogen

The antiserum was produced against synthesized peptide derived from human PKG2.

Immunogen Range: 92-141

Biochem./physiol. Wirkung

Type II cGMP-dependent protein kinase (PRKG2) is implicated in the regulation of intestinal fluid balance in humans. The encoded protein plays an essential role in proliferative to hypertrophic transition of growth plate chondrocytes during endochondral ossification. Loss of PRKG2 function is associated with the development of renal cysts, intellectual disability and speech defect. In rodent and bovine models, deletion of the gene leads to dwarfism.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable