SAB4500935

Anti-FOXO1 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): FKHR, FOXO1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma, forkhead box O1A (FKHR)
• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ELISA, IHC
• Citations: 5

Eigenschaften

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 69 kDa
• species reactivity: mouse, human
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:1000, immunohistochemistry: 1:50-1:100
• NCBI accession no.: Q12778
• UniProt accession no.: Q12778
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... FOXO1(2308)

Beschreibung

General description

Anti-FOXO1 Antibody detects endogenous levels of total FOXO1 protein.

FOXO1 (forkhead box O1) encodes a forkhead transcription factor that belongs to the Foxo subfamily. It is located on human chromosome 13q14. FOXO1 is abundantly expressed in adult pancreas and partially expressed in pancreatic β cells.

Immunogen

The antiserum was produced against synthesized peptide derived from human FOXO1/3/4.

Immunogen Range: 15-64

Biochem/physiol Actions

FOXO1 (forkhead box O1) blocks the separation of cell in fetal pancreatic progenitor cells. It controls the differentiation of adipocyte. It plays a major role in the development and multiplication of β cell. It plays an important role in transferring insulin signaling downstream of protein kinase B.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable