SAB4301041

Anti-CD163 antibody produced in rabbit

affinity isolated antibody

• Synonym(e): M130, MM130
• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: rabbit
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Konzentration: 2.9 mg/mL
• Methode(n): immunohistochemistry: 1:25- 1:100
• Isotyp: IgG
• Hinterlegungsnummer: NP_004235.4
• UniProt-Hinterlegungsnummer: Q86VB7
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CD163(9332)

Beschreibung

Allgemeine Beschreibung

Cluster of differentiation 163 (CD163) is a hemoglobin scavenger receptor, encoded by a gene mapped to human chromosome 12p13.31. It is expressed on the surface of activated macrophages. The encoded protein is a member of scavenger receptor cysteine-rich family (SRCR) and is specifically expressed on cells of the monocyte/macrophage lineage.

Spezifität

The antibody detects endogenous levels of total CD163 protein.

Immunogen

Synthetic peptide corresponding to residues near the C terminal of human CD163 molecule

Biochem./physiol. Wirkung

Cluster of differentiation 163 (CD163) modulates anti-inflammatory functions and has a role in hemoglobin-haptoglobin clearance. Various cytokines influence the expression of CD163. It may be associated with hepatocellular carcinoma. Soluble CD163 level in serum acts as a potent indicator of the progression of cirrhosis and portal hypertension.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in pH7.3 PBS, 0.05% NaN₃, 50% Glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable