SAB4100383

Monoclonal Anti-TMOD1 antibody produced in mouse

clone TMOD1-A328, culture supernatant

• Synonym(e): Anti-D9S57E, Anti-ETMOD, Anti-TMOD, Anti-tropomodulin 1
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Konjugat: unconjugated
• Antikörperform: culture supernatant
• Antikörper-Produkttyp: primary antibodies
• Klon: TMOD1-A328, monoclonal
• Form: aqueous solution
• Mol-Gew.: antigen predicted mol wt 40.4 kDa
• Speziesreaktivität: human
• Methode(n): western blot: suitable
• Isotyp: IgG2b
• UniProt-Hinterlegungsnummer: P28289
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... TMOD1(7111)

Beschreibung

Allgemeine Beschreibung

Tropomodulin 1 (TMOD1) is an actin-capping protein, which is expressed in the cardiac muscle and in slow-twitch muscle fibers. It possesses two actin- and two tropomyosin (TM)-binding regions. The gene encoding this protein is localized on human chromosome 9q.

Immunogen

TMOD1 purified recombinant protein

Biochem./physiol. Wirkung

Tropomodulin 1 (TMOD1) prevents the elongation and depolymerization of actin filaments by binding to the slowly growing pointed end of the actin filament. It has been associated with triple-negative breast cancers (TNBC). TMOD1 may act as a stabilizer of β-catenin.

Physikalische Form

Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable