Alle Fotos(1)
Wichtige Dokumente
S3884
Sauvagine
≥97% (HPLC)
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Alle Fotos(1)
About This Item
Empirische Formel (Hill-System):
C202H346N56O63S
CAS-Nummer:
Molekulargewicht:
4599.31
MDL-Nummer:
UNSPSC-Code:
12352200
NACRES:
NA.32
Assay
≥97% (HPLC)
Lagertemp.
−20°C
InChIKey
ILCVKEBXPLEGOY-ZLFMSJRASA-N
Amino Acid Sequence
Glp-Gly-Pro-Pro-Ile-Ser-Ile-Asp-Leu-Ser-Leu-Glu-Leu-Leu-Arg-Lys-Met-Ile-Glu-Ile-Glu-Lys-Gln-Glu-Lys-Glu-Lys-Gln-Gln-Ala-Ala-Asn-Asn-Arg-Leu-Leu-Leu-Asp-Thr-Ile-NH2
Allgemeine Beschreibung
Biochem./physiol. Wirkung
A peptide related to CRF and urotensin 1 that was first isolated from the skin of the frog Phyllomedusa sauvagei. Potent releaser of ACTH and β-endorphin from the anterior pituitary.
Sonstige Hinweise
Lyophilized from 0.1% TFA in H2O
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Kostas Gkountelias et al.
Molecular pharmacology, 78(4), 785-793 (2010-07-29)
Family B of G protein-coupled receptors (GPCRs) is composed of receptors that bind peptides, such as secretin, glucagon, parathyroid hormone, and corticotropin releasing factor (CRF), which play critical physiological roles. These receptors, like all GPCRs, share a common structural motif
T Renda et al.
Archives of histology and cytology, 52 Suppl, 317-323 (1989-01-01)
The authors present an overview of the main amphibian peptide families mainly derived from the skin and mostly discovered by Erspamer and his associates. The studies of the peptides do not only promote the understanding of their chemical, metabolical and
Takeshi Nakamura et al.
American journal of physiology. Heart and circulatory physiology, 296(2), H325-H332 (2008-12-09)
Urocortin 3 (Ucn3) is a new member of the corticotropin-releasing factor (CRF) peptide family and is considered to be a specific and endogenous ligand for CRF type 2 receptors (CRF2Rs). The presence of CRF(2)Rs has been reported in the nucleus
Lisa Frommelt et al.
Peptides, 39, 111-118 (2012-12-04)
Studies have shown a reduction of food intake following peripheral and brain injection of CCK. However, it remains to be established whether endogenous central CCK is involved in the regulation of food intake. We investigated the role of central CCK
Eric Gutknecht et al.
Journal of neurochemistry, 104(4), 926-936 (2007-11-03)
Endogenous expression of the corticotropin-releasing factor type 2a receptor [CRF2(a)] but not CRF2(b) and CRF2(c) was observed in higher passage cultures of human Y79 retinoblastoma cells. Functional studies further demonstrated an increase in CRF2(a) mRNA and protein levels with higher
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