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RAB0642

Sigma-Aldrich

Human F3 / Tissue Factor ELISA Kit

Synonym(e):

Coagulation factor III, TF, Thromboplastin, Tissue factor 

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About This Item

UNSPSC-Code:
41116158
NACRES:
NA.32

Speziesreaktivität

human

Verpackung

kit of 96 wells (12 strips x 8 wells)

Methode(n)

ELISA: suitable

Aufnahme

sample type cell culture supernatant(s)
sample type serum
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 6 pg/mL
standard curve range: 6.14-1500 pg/mL

Nachweisverfahren

colorimetric

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... F3(2152)

Verwandte Kategorien

Allgemeine Beschreibung

The antibody pair provided in this kit recognizes human Coagulation Factor III/Tissue Factor.

Tissue factor (TF), also known as coagulation factor III (F3), is encoded by the gene mapped to human chromosome 1p21.3. TF has been shown to exist in two forms, namely membrane-bound and soluble TF. The encoded protein contains an extracellular domain (ED), a single transmembrane domain (TD) and short cytoplasmic domain (CD).

Anwendung

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Human F3 / Tissue Factor ELISA Kit has been used to measure the concentration of soluble tissue factor (TF) expressed in human umbilical vein smooth muscle cells (HUVSMCs).

Biochem./physiol. Wirkung

Tissue factor (TF) interacts with the zymogen factor VII (VII) and its activated form VIIa, and initiates blood coagulation protease cascade. The encoded protein is involved in the pathogenesis of cardiovascular diseases, such as hypertension, atherosclerosis, acute coronary syndrome and restenosis. Thus, it is considered to be a potential therapeutic target for cardiovascular diseases.

Kit-Komponenten auch einzeln erhältlich

Produkt-Nr.
Beschreibung
SDB
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDB
  • RABSTOP3ELISA Stop Solution (Item I)SDB
  • RABWASH420X Wash Buffer (Item B)SDB

Piktogramme

Corrosion
GHS05

Signalwort

Warning

H-Sätze

H290

P-Sätze

P234 - P390

Gefahreneinstufungen

Met. Corr. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Zulassungslistungen

Zulassungslistungen werden hauptsächlich für chemische Produkte erstellt. Für nicht-chemische Produkte können hier nur begrenzte Angaben gemacht werden. Kein Eintrag bedeutet, dass keine der Komponenten gelistet ist. Es liegt in der Verantwortung des Benutzers, die sichere und legale Verwendung des Produkts zu gewährleisten.

EU REACH Annex XVII (Restriction List)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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