PZ0175

PD 149163 tetrahydrochloride hydrate

≥90% (HPLC)

• Synonym(e): N2-[(2S)-2,6-Diaminohexyl]-L-lysyl-L-prolyl-L-tryptophyl-3-methyl-L-valyl-L-Leucine ethyl ester tetrahydrochloride hydrate
• Empirische Formel (Hill-System): C₄₂H₇₁N₉O₆·4HCl · xH₂O
• Molekulargewicht: 943.91 (anhydrous basis)
• NACRES: NA.77
• PubChem Substance ID: 329823749
• UNSPSC Code: 12352200
• MDL number: MFCD20527308
• Assay: ≥90% (HPLC)
• Form: powder (Hygroscopic)
• Storage condition: desiccated

Eigenschaften

• assay: ≥90% (HPLC)
• form: powder (Hygroscopic)
• storage condition: desiccated
• color: white to tan
• solubility: H₂O: ≥12 mg/mL
• storage temp.: 2-8°C
• SMILES string: O.Cl.Cl.Cl.Cl.CCOC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CCCCN)NC[C@@H](N)CCCCN)C(C)(C)C
• InChI: 1S/C42H71N9O6.4ClH.H2O/c1-7-57-41(56)34(23-27(2)3)49-39(54)36(42(4,5)6)50-37(52)33(24-28-25-46-31-17-9-8-16-30(28)31)48-38(53)35-19-14-22-51(35)40(55)32(18-11-13-21-44)47-26-29(45)15-10-12-20-43;;;;;/h8-9,16-17,25,27,29,32-36,46-47H,7,10-15,18-24,26,43-45H2,1-6H3,(H,48,53)(H,49,54)(H,50,52);4*1H;1H2/t29-,32-,33-,34-,35-,36+;;;;;/m0...../s1
• InChI key: PIFVEGOSSWCHFK-AEPODNBTSA-N

Beschreibung

Biochem/physiol Actions

PD 149163 is a Neurotensin NTR1 receptor agonist; a Neurotensin (8-13) analog. PD149163 is a selective, brain penetrating NT1 receptor agonist with pro-cognitive, antipsychotic and anxiolytic effects.

PD 149163 is a neurotensin (8-13) analog; Neurotensin NTR1 receptor agonist

Features and Benefits

This compound is featured on the Neurotensin Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable