PLA0234

Rabbit anti-BCR Antibody, Affinity Purified

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• Synonym(e): ALL, BCR/FGFR1 chimera protein, BCR1, CML, D22S11, D22S662, FGFR1/BCR chimera protein, PHL, breakpoint cluster region, renal carcinoma antigen NY-REN-26
• NACRES: NA.41
• UNSPSC Code: 12352203

Eigenschaften

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• species reactivity: human
• technique(s): flow cytometry: 0.5 μg, immunofluorescence: 1:500- 1:2,000, immunoprecipitation (IP): 10 μg/mg, western blot: 1:2,000- 1:10,000
• accession no.: NP_004318.3
• UniProt accession no.: P11274
• shipped in: wet ice
• storage temp.: 2-8°C
• Gene Information: rabbit ... BCR(613)

Beschreibung

Immunogen

The epitope recognized by PLA0234 maps to a region between residue 1221 and 1271 of human breakpoint cluster region using the numbering given in entry NP_004318.3 (GeneID 613).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

BCR (breakpoint cluster region) was identified as part of a fusion protein that results from a reciprocal translocation with the ABL gene between chromosomes 22 and 9. The BCR-ABL fusion is the cause of chronic myeloid leukemia (CML). The BCR protein contains a C2 domain, a DBL-homology domain, a PH domain, and a Rho-GAP domain and functions as a GTPase-activating protein for RAC1 and CDC42.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable