PLA0110

Rabbit anti-LATS2 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• UNSPSC Code: 12352203

Eigenschaften

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• species reactivity: mouse, human
• technique(s): immunoprecipitation (IP): 2-10 μg/mg, western blot: 1:1,000- 1:5,000
• accession no.: NP_055387.1
• UniProt accession no.: Q9NRM7
• shipped in: wet ice
• storage temp.: 2-8°C
• Gene Information: rabbit ... LATS2(26524)

Beschreibung

Immunogen

The epitope recognized by PLA0110 maps to a region between residues 1 and 50 of human Large Tumor Suppressor 2 using the numbering given in entry NP_055387.1 (GeneID 26524).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

LATS2 (Large Tumor Suppressor homolog 2) has been identified as a tumor suppressor protein and is a member of the Dbf2-related (NDR) family of protein kinases that are key components of the mitotic exit network. LATS2 appears to negatively regulate G2/M transitioning by down-regulating CDC2 kinase activity. LATS2 has also been identified as a negative regulator of the androgen receptor (AR) and may play a role in AR-mediated transcription and the development of prostate cancer.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable