PLA0077

Rabbit anti-53BP1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(e): 1, 53BP1, TDRD30, TP53, p202, p53-binding protein 1, p53BP1, tumor protein 53-binding protein, tumor protein p53-binding protein
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Qualität: Powered by Bethyl Laboratories, Inc.
• Speziesreaktivität: human, mouse
• Methode(n): western blot: 1:2,000-1:10,000
• Hinterlegungsnummer: NP_005648.1
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Angaben zum Gen: rabbit ... 53BP1(7158)

Beschreibung

Immunogen

The epitope recognized by PLA0077 maps to a region between residues 1925 and the C-terminus (residue 1972) of human tumor protein p53 binding protein 1 using the numbering given in entry NP_005648.1 (GeneID 7158).

Physikalische Form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Sonstige Hinweise

53BP1 (p53 Binding Protein 1) is an early participant in the cellular response to DNA double-strand breaks. 53BP1 functions in a redundant role in phosphorylation of the downstream checkpoint effector proteins Brca1 and Chk2 but was required for the formation of Brca1 foci in a hierarchical branched pathway for the recruitment of repair and signaling proteins to sites of DNA damage.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable