P7547

Phentolamin -hydrochlorid

≥98% (TLC), α-adrenoceptor antagonist, powder

• Synonym(e): 2-[N-(3-Hydroxyphenyl)-4-toluidinomethyl]-2-imidazolin -hydrochlorid, 3-[[(4,5-Dihydro-1H-imidazol-2-yl)-methyl](4-methylphenyl)-amino]-phenol -monohydrochlorid
• Empirische Formel (Hill-System): C₁₇H₁₉N₃O · HCl
• CAS-Nummer: 73-05-2
• Molekulargewicht: 317.81
• NACRES: NA.77
• PubChem Substance ID: 24898856
• UNSPSC Code: 12352116
• EC Number: 200-793-5
• MDL number: MFCD00079268
• Beilstein/REAXYS Number: 3764617
• Assay: ≥98% (TLC)
• Form: powder

Eigenschaften

• Produktname: Phentolamin -hydrochlorid, ≥98% (TLC), powder
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder
• color: white to off-white
• solubility: ethanol: 14 mg/mL, H₂O: 20 mg/mL, H₂O: unstable (prepare immediately prior to use)
• originator: Novartis
• SMILES string: Cl[H].Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3
• InChI: 1S/C17H19N3O.ClH/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H
• InChI key: TUEJFGFQYKDAPM-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

Beschreibung

Biochem/physiol Actions

α-Adrenoceptor-Antagonist; peripherer Vasodilator

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Protect From Light.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves