P2508

Proflavin -hemisulfat (Salz) Hydrat

powder

• Synonym(e): 3,6-Diamino-acridin -hemisulfat (Salz)
• Empirische Formel (Hill-System): C₁₃H₁₁N₃ · 0.5 H₂SO₄ · xH₂O
• CAS-Nummer: 1811-28-5
• Molekulargewicht: 258.29 (anhydrous basis)
• UNSPSC Code: 12171500
• NACRES: NA.47
• PubChem Substance ID: 24898329
• EC Number: 217-320-3
• Beilstein/REAXYS Number: 3921806
• MDL number: MFCD00149650

Eigenschaften

• form: powder
• Quality Segment: 100
• solubility: H₂O: 10 mg/mL
• fluorescence: λ_ex 444 nm; λ_em 508 nm (0.01M HCl)
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: [H]O[H].OS(O)(=O)=O.Nc1ccc2cc3ccc(N)cc3nc2c1.Nc4ccc5cc6ccc(N)cc6nc5c4
• InChI: 1S/2C13H11N3.H2O4S.H2O/c2*14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;1-5(2,3)4;/h2*1-7H,14-15H2;(H2,1,2,3,4);1H2
• InChI key: DTRLDKDFCPUGCA-UHFFFAOYSA-N

Beschreibung

General description

Proflavine is a small, amphipathic, acridine-derived fluorescent dye.Proflavine hemisulfate is used as a rapid stain for cytological studies of biological specimens. It stains cytoplasmic structures and nuclei. Proflavine has the capability to intercalate double stranded DNA.

Application

Proflavine hemisulfate salt hydrate has been used to stain cells of the 1483 cell line. It has also been used as a calibrating dye in fluorescence resonance energy transfer (FRET) analysis.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335
• pcodes: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves