P2508

Proflavin -hemisulfat (Salz) Hydrat

powder

• Synonym(e): 3,6-Diamino-acridin -hemisulfat (Salz)
• Empirische Formel (Hill-System): C₁₃H₁₁N₃ · 0.5 H₂SO₄ · xH₂O
• CAS-Nummer: 1811-28-5
• Molekulargewicht: 258.29 (anhydrous basis)
• Beilstein: 3921806
• EG-Nummer: 217-320-3
• MDL-Nummer: MFCD00149650
• UNSPSC-Code: 12171500
• PubChem Substanz-ID: 24898329
• NACRES: NA.47

Eigenschaften

• Form: powder
• Löslichkeit: H₂O: 10 mg/mL
• Fluoreszenz: λ_ex 444 nm; λ_em 508 nm (0.01M HCl)
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: room temp
• SMILES String: [H]O[H].OS(O)(=O)=O.Nc1ccc2cc3ccc(N)cc3nc2c1.Nc4ccc5cc6ccc(N)cc6nc5c4
• InChI: 1S/2C13H11N3.H2O4S.H2O/c2*14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10;1-5(2,3)4;/h2*1-7H,14-15H2;(H2,1,2,3,4);1H2
• InChIKey: DTRLDKDFCPUGCA-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Proflavine is a small, amphipathic, acridine-derived fluorescent dye.Proflavine hemisulfate is used as a rapid stain for cytological studies of biological specimens. It stains cytoplasmic structures and nuclei. Proflavine has the capability to intercalate double stranded DNA.[1]

Anwendung

Proflavine hemisulfate salt hydrate has been used to stain cells of the 1483 cell line.[2] It has also been used as a calibrating dye in fluorescence resonance energy transfer (FRET) analysis.[3]

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves