P207

Philanthotoxin 433 tris(trifluoroacetate) salt

≥98% (HPLC), powder

• Synonym(e): (S)-N-[4-[[3-[(3-Aminopropyl)amino]propyl]amino]butyl]-4-hydroxy-α-[(1-oxobutyl)amino]benzenepropanamide tris(trifluoroacetate) salt, PhTX-433 tris(trifluoroacetate) salt
• Empirische Formel (Hill-System): C₂₃H₄₁N₅O₃ · 3C₂HF₃O₂
• CAS-Nummer: 276684-27-6
• Molekulargewicht: 777.67
• MDL-Nummer: MFCD00661076
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 24898269

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: H₂O: ≥10 mg/mL
• Lagertemp.: −20°C
• SMILES String: OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCCCNCCCNCCCN
• InChI: 1S/C23H41N5O3.3C2HF3O2/c1-2-7-22(30)28-21(18-19-8-10-20(29)11-9-19)23(31)27-17-4-3-13-25-15-6-16-26-14-5-12-24;3*3-2(4,5)1(6)7/h8-11,21,25-26,29H,2-7,12-18,24H2,1H3,(H,27,31)(H,28,30);3*(H,6,7)/t21-;;;/m0.../s1
• InChIKey: UROZAUWUTBOQNV-YDULTXHLSA-N
• Angaben zum Gen: human ... GRIN1(2902) ; mouse ... GRIN1(14810) ; rat ... GRIN1(24408)

Beschreibung

Biochem./physiol. Wirkung

Philanthotoxin 433 is a polyamine-containing toxin, which blocks NMDA-gated ion channels; originally isolated from the venom of the wasp Philanthus triangulum.

Vorsicht

hygroscopic

Rekonstituierung

Addition of 1 mL of solvent to vial yields a 1 mM solution.

Rechtliche Hinweise

Sold under license from Columbia University.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301
• P-Sätze: P301 + P310
• Gefahreneinstufungen: Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)