P0080

Pranlukast hemihydrate

≥98% (HPLC), CysLT1 receptor antagonist, solid

• Synonym(e): 8-[4(4-phenylbutoxy)benzoyl]amino-2-(5-tetrazolyl)-4-oxo-4H-1-benzopyran
• Empirische Formel (Hill-System): C₂₇H₂₃N₅O₄ · 0.5 H₂O
• CAS-Nummer: 150821-03-7
• Molekulargewicht: 490.51
• UNSPSC Code: 51111800
• PubChem Substance ID: 329820009
• NACRES: NA.77
• MDL number: MFCD24539454
• Assay: ≥98% (HPLC)
• Form: solid
• Quality level: 100

Eigenschaften

• Produktname: Pranlukast hemihydrate, ≥98% (HPLC), white, solid
• Quality Level: 100
• assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: DMSO: ≥10 mg/mL, H₂O: insoluble
• storage temp.: −20°C
• SMILES string: O.O=C(Nc1cccc2C(=O)C=C(Oc12)c3nnn[nH]3)c4ccc(OCCCCc5ccccc5)cc4.O=C(Nc6cccc7C(=O)C=C(Oc67)c8nnn[nH]8)c9ccc(OCCCCc%10ccccc%10)cc9
• InChI: 1S/2C27H23N5O4.H2O/c2*33-23-17-24(26-29-31-32-30-26)36-25-21(23)10-6-11-22(25)28-27(34)19-12-14-20(15-13-19)35-16-5-4-9-18-7-2-1-3-8-18;/h2*1-3,6-8,10-15,17H,4-5,9,16H2,(H,28,34)(H,29,30,31,32);1H2
• InChI key: MSXTUBJFNBZPGC-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Pranlukast is a subtype specific CysLT1 receptor antagonist.

Pranlukast is a subtype specific CysLT1 receptor antagonist. Leukotrienes are involved in the inflammation response and are divided into two main classes; leukotriene B4 and cysteinyl-substituted leukotrienes.

Features and Benefits

This compound is featured on the Leukotriene Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335,H413
• pcodes: P273 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves