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Merck

N9879

Sigma-Aldrich

NADase from porcine brain

≥0.007 unit/mg solid

Synonym(e):

DPN Nucleosidase, NAD+ glycohydrolase

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About This Item

CAS-Nummer:
EC-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352204
NACRES:
NA.54

Form

powder

Spezifische Aktivität

≥0.007 unit/mg solid

Löslichkeit

insoluble

Lagertemp.

−20°C

Allgemeine Beschreibung

NADase is a glycohydrolase that catalyzes ADP-ribose transfer.

Anwendung

NADase from porcine brain has been used in a study to investigate histidine and related compounds resulting from catalyzed ADP-riboslyation. It has also been used in a study to investigate the preparation of arylazide-substituted pyridine adenine dinucleotides for photoaffinity labeling.

Biochem./physiol. Wirkung

Nicotinamide has been shown to inhibit NADase activity.

Einheitendefinition

One unit will hydrolyze 1.0 μmole of β-NAD to nicotinamide and ADP-ribose per min at pH 7.3 at 37 °C.

Physikalische Form

Acetone-dried powder

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Nicholas Chiorazzi
Hematology. American Society of Hematology. Education Program, 2012, 76-87 (2012-12-13)
Several prognostic markers based on genetic, phenotypic, and molecular characteristics of chronic lymphocytic leukemia (CLL) B cells have emerged in the past decade. The clinical utility of these newer prognostic indicators, alone or in combination with each other and other
Ding-bao Chen et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 41(9), 607-612 (2012-11-20)
To study the clinical and histopathologic features, diagnosis, pathogenesis and therapy of post-transplant lymphoproliferative disorders (PTLD). The clinical and pathologic features of 15 cases of PTLD were retrospectively analyzed by light microscopy, immunohistochemistry and in-situ hybridization, according to the updated
Shoko Nakayama et al.
Hematology (Amsterdam, Netherlands), 17(6), 317-320 (2012-11-22)
The accurate determination of cytoplasmic immunoglobulin (cIg) light chain (LC) expression is important to differentiate reactive plasmacytosis from a clonal plasma cell neoplasm such as plasma cell myeloma (PCM). Through retrospective analysis, we studied the cytoplasmic kappa/lambda ratio of CD38-positive
K A Wall et al.
The Biochemical journal, 335 ( Pt 3), 631-636 (1998-10-31)
Carba-NAD and pseudocarba-NAD are carbocyclic analogues of NAD+ in which a 2,3-dihydroxycyclopentane methanol replaces the beta-d-ribonucleotide ring of the nicotinamide riboside moiety of NAD+ [Slama and Simmons (1988) Biochemistry 27, 183-193]. These carbocyclic NAD+ analogues, related to each other as
Preparation and Evaluation of Arylazide-Substituted Pyridine Adenine Dinucleotides for Photoaffinity Labeling Experiments
Liu, W., et al.
Photochemistry and Photobiology, 63, 793-799 (1996)

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