M9318

Anti-Melanocortin 4 Receptor antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-MC4R
• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD02263636
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ICC, IHC (p)
• Citations: 3

Eigenschaften

• biological source: rabbit
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• availability: not available in Japan
• technique(s): immunocytochemistry: 4 μg/mL using human brain, caudate, immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4 μg/mL using human brain, caudate
• UniProt accession no.: P32245
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... MC4R(4160) ; mouse ... Mc4r(17202) ; rat ... Mc4r(25635)

Beschreibung

Immunogen

synthetic peptide corresponding to the N-terminal extracellular domain of human melanocortin 4 receptor. The immunizing peptide has 94% homology with the rat and mouse gene.

Biochem/physiol Actions

Melanocortin 4 receptor (MC4R) is an important regulator of food intake and body weight in mammals. It also regulates energy homeostasis in response to neuropeptides. Polymorphisms in MC4R gene or haploinsufficiency results in early onset obesity in humans also termed melanocortin obesity syndrome.

Physical form

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable