M5404

Morantel citrate salt

• Synonym(e): 1,4,5,6-Tetrahydro-1-methyl-2-(2-[3-methyl-2-thienyl]ethenyl)pyrimidine
• Empirische Formel (Hill-System): C₁₂H₁₆N₂S · C₆H₈O₇
• CAS-Nummer: 69525-81-1
• Molekulargewicht: 412.46
• EG-Nummer: 274-028-9
• MDL-Nummer: MFCD00079447
• UNSPSC-Code: 51101500
• PubChem Substanz-ID: 329818012

Eigenschaften

• Farbe: yellow
• Löslichkeit: H₂O: 4.0 mL, clear, yellow-green (200 mg + 4.0 mL H2O)
• Wirkungsspektrum von Antibiotika: parasites
• Wirkungsweise: enzyme | inhibits
• SMILES String: OC(=O)CC(O)(CC(O)=O)C(O)=O.CN1CCCN=C1\C=C\c2sccc2C
• InChI: 1S/C12H16N2S.C6H8O7/c1-10-6-9-15-11(10)4-5-12-13-7-3-8-14(12)2;7-3(8)1-6(13,5(11)12)2-4(9)10/h4-6,9H,3,7-8H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b5-4+;
• InChIKey: OLOCXIJVDIVAHH-FXRZFVDSSA-N

Beschreibung

Anwendung

Morantel is a anthelmintic compound used to treat parasitic infections in livestock. It is also used to study allosteric potentiation of rat neuronal nicotinic acetylcholine receptors (nAChRs) and is used to study nematode nicotinic receptors.

Biochem./physiol. Wirkung

Morantel is a potent non-canonical (binding site) acetylcholine (ACh) receptor agonist and inhibits fumarate reductase.

Morantel is a potent non-canonical (binding site) acetylcholine (ACh) receptor agonist and inhibits fumarate reductase. Morantel increases the macroscopic currents evoked by acetylcholine (ACh) from nAChRs expressed in Xenopus laevis oocytes up to 8 times.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332
• P-Sätze: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves