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M3404

(±)-p-Methoxyamphetamin -hydrochlorid

Name: (±)-p-Methoxyamphetamin -hydrochlorid
Brand: SIGMA

Synonym(e):

PMA -hydrochlorid

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About This Item

Empirische Formel (Hill-System):

C₁₀H₁₅NO · HCl

CAS-Nummer:

52740-56-4

Molekulargewicht:

201.69

MDL-Nummer:

MFCD00051431

UNSPSC-Code:

12352200

PubChem Substanz-ID:

24896840

Arzneimittelkontrolle

USDEA Schedule I; Home Office Schedule 1; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
veterinary

SMILES String

Cl.COc1ccc(CC(C)N)cc1

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Biochem./physiol. Wirkung

CNS stimulant and hallucinogen; more potent transport inhibitor and releaser of serotonin than of dopamine.

Piktogramme

GHS06

Signalwort

Danger

H-Sätze

H301

P-Sätze

P301 + P310

Gefahreneinstufungen

Acute Tox. 3 Oral

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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4-Ethoxyamphetamine: effects on intracranial self-stimulation and in vitro uptake and release of 3H-dopamine and 3H-serotonin in the brains of rats.

K M Hegadoren et al.

Journal of psychiatry & neuroscience : JPN, 19(1), 57-62 (1994-01-01)

Experiments were conducted to compare the effects of 4-ethoxyamphetamine, a novel "designer" amphetamine, with (+)-amphetamine and an earlier "designer" amphetamine, 4-methoxyamphetamine, on rats. (+)-Amphetamine significantly decreased frequency threshold measures in an intracranial self-stimulation (ICSS) procedure using medial forebrain bundle electrodes

Interactions of amphetamine analogs with human liver CYP2D6.

D Wu et al.

Biochemical pharmacology, 53(11), 1605-1612 (1997-06-01)

The interaction of fifteen amphetamine analogs with the genetically polymorphic enzyme CYP2D6 was examined. All fourteen phenylisopropylamines tested were competitive inhibitors of CYP2D6 in human liver microsomes. The presence of a methylenedioxy group in the 3,4-positions of both amphetamine (Ki

Selective electrochemical discrimination between dopamine and phenethylamine-derived psychotropic drugs using electrodes modified with an acyclic receptor containing two terminal 3-alkoxy-5-nitroindazole rings.

Antonio Doménech et al.

The Analyst, 135(6), 1449-1455 (2010-04-22)

Electrochemical discrimination between dopamine and psychotropic drugs which have in common a skeletal structure of phenethylamine, can be obtained using acyclic receptors L(1) and L(2), containing two terminal 3-alkoxy-5-nitroindazole rings. Upon attachment to graphite electrodes, L(1) and L(2) exhibit a

The effects of co-administration of 3,4-methylenedioxymethamphetamine ("ecstasy") or para-methoxyamphetamine and moclobemide at elevated ambient temperatures on striatal 5-HT, body temperature and behavior in rats.

N Stanley et al.

Neuroscience, 146(1), 321-329 (2007-02-20)

We have recently demonstrated that co-administration of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") with the reversible monoamine oxidase type A (MAO-A) inhibitor moclobemide at an ambient temperature of 22 degrees C significantly increases striatal 5-HT outflow and 5-HT-mediated behaviors. In the present study

Simultaneous determination of 13 amphetamine related drugs in human whole blood using an enhanced polymer column and gas chromatography-mass spectrometry.

Keiko Kudo et al.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 855(1), 115-120 (2007-04-04)

Metamphetamine (MA) is one of the most frequently encountered abused drugs in Japan and the Triage immunoassay kit is often used to screen for this drug. However, immunoassay screening also gives positive results with other structurally related compounds, such as

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