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M2295
Myelin Basic Protein from guinea pig brain
≥80% (SDS-PAGE), lyophilized powder, from guinea pig brain
Synonym(e):
MBP
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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 mg | Warenkorb auf Verfügbarkeit prüfen | € 312,00 |
5 mg | Warenkorb auf Verfügbarkeit prüfen | € 1.020,00 |
Über diesen Artikel
Form:
lyophilized powder
Assay:
≥80% (SDS-PAGE)
Biological source:
guinea pig brain
Technischer Dienst
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Unterstützung erhaltenbiological source
guinea pig brain
Quality Segment
assay
≥80% (SDS-PAGE)
form
lyophilized powder
technique(s)
cell based assay: suitable
UniProt accession no.
application(s)
cell analysis
storage temp.
−20°C
Gene Information
guinea pig ... MBP(100731253)
General description
Myelin Basic Protein (MBP) expressed in guinea pig brain contains 167 amino acids and has a molecular weight of 18,256Da.
Research area: Cell SignallingMyelin basic protein (MBP) is an important constituent of the myelin sheath of CNS (central nervous system). It is an auto-immunogen.
Application
Biochem/physiol Actions
Major structural protein of CNS myelin. Used to induce experimental allergic encephalomyelitis.
Mutation of the myelin basic protein gene induces dysmyelination; used to induce experimental allergic encephalomyelitis.
Used as a kinase substrate.
Myelin basic protein (MBP) plays a vital role in formation of myelin sheath and is associated with the various neurological disorders. MBP function as an antigenic target in autoimmune disease experimental allergic encephalomyelitis (EAE). MBP plays an essential role in cytoskeletal turnover and membrane extension. Additionally, it is also involved in Fyn-mediated signaling pathways, sequestration of phosphoinositides and regulation of calcium homoeostasis. MBP functions as an in vitro substrate for mitogen-activated protein kinase (MAP) kinase and aids in the purification and functional studies of enzyme.
Analysis Note
May contain traces of urea-glycine buffer salts.
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Dieser Artikel | |||
|---|---|---|---|
| assay ≥80% (SDS-PAGE) | assay ≥97% (HPLC) | assay ≥95% (SDS-PAGE) | assay ≥90% (SDS-PAGE) |
| biological source guinea pig brain | biological source - | biological source human brain | biological source bovine |
| technique(s) cell based assay: suitable | technique(s) - | technique(s) ELISA: suitable | technique(s) activity assay: suitable |
| form lyophilized powder | form - | form lyophilized powder | form lyophilized powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −20°C |
| UniProt accession no. | UniProt accession no. - | UniProt accession no. | UniProt accession no. |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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