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Merck

GW22651

Sigma-Aldrich

Anti-Spondin-1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

chicken

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

human, rat, mouse

Hersteller/Markenname

Genway 15-288-22651

Methode(n)

western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... SPON1(10418)

Immunogen

Immunogen Sequence: GI # 24307905, sequence 549-807
Recombinant spondin 1, extracellular matrix protein

Anwendung

Anti-Spondin-1 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem./physiol. Wirkung

Spondin-1 (also known as F-spondin) is a protein encoded by the SPON1 gene in humans. It is an extracellular matrix protein that mediates axon guidance during neuronal development and consists of an N-terminal domain called as reelin-N domain. F-spondin highly expressing human periodontal ligament (HPL) cells show similar phenotype of cementoblasts. It acts as a promoting factor for cementoblastic differentiation.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Die Dokumentenbibliothek aufrufen

Masae Kitagawa et al.
Biochemical and biophysical research communications, 349(3), 1050-1056 (2006-09-13)
Cementum is a mineralized tissue produced by cementoblasts covering the roots of teeth that provides for the attachment of periodontal ligament to roots and surrounding alveolar bone. To study the mechanism of proliferation and differentiation of cementoblasts is important for
Kemin Tan et al.
Journal of molecular biology, 381(5), 1213-1223 (2008-07-08)
The extracellular matrix protein F-spondin mediates axon guidance during neuronal development. Its N-terminal domain, termed the reelin-N domain, is conserved in F-spondins, reelins, and other extracellular matrix proteins. In this study, a recombinant human reelin-N domain has been expressed, purified

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