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GW21071

Anti-PI3K antibody produced in chicken

Name: Anti-PI3K antibody produced in chicken
Brand: SIGMA

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit β isoform

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About This Item

UNSPSC-Code:

12352203

NACRES:

NA.41

Biologische Quelle

chicken

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Speziesreaktivität

rat, mouse, human

Methode(n)

western blot: suitable

NCBI-Hinterlegungsnummer

NP_006210.1

UniProt-Hinterlegungsnummer

P42338

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... PIK3CB(5291)

Immunogen

Immunogen Sequence: GI # 5453894, sequence 58-134

Recombinant phosphoinositide-3-kinase, catalytic, β polypeptide

Anwendung

Anti-PI3K antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem./physiol. Wirkung

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit β isoform is an enzyme encoded by the PIK3CB gene in humans. It has been implicated as a participant in signaling pathways regulating cell growth by virtue of its activation in response to various mitogenic stimuli. PI 3-kinase exhibits different isoforms and has a define family of genes encoding distinct PI 3-kinase catalytic subunits that can associate with p85. It is commonly activated in tumors. PI3K pathway is activated in tumors and most commonly through p110α mutation or PTEN deletion.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Analysenzertifikate (COA)

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Hashem A Dbouk et al.

PloS one, 8(5), e63833-e63833 (2013-06-05)

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Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85.

P Hu et al.

Molecular and cellular biology, 13(12), 7677-7688 (1993-12-01)

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