Based on a molecular formula of C5H10N2O3, the molecular weight to seven significant figures is 146.1456. Over the years, this value may have been reported in Sigma-Aldrich documentation or on labels as either 146.15 (by rounding up) or 146.14 (by truncation). The material itself has not changed.
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G6392
L -Glutamin
γ-irradiated, BioXtra, suitable for cell culture
Synonym(e):
(S)-2,5-Diamino-5-oxopentansäure,
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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
1 vial | Warenkorb auf Verfügbarkeit prüfen | € 24,30 |
10 vials | Warenkorb auf Verfügbarkeit prüfen | € 269,00 |
Über diesen Artikel
Lineare Formel:
H2NCOCH2CH2CH(NH2)CO2H
CAS-Nummer:
Molekulargewicht:
146.14
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
EC Number:
200-292-1
NACRES:
NA.75
Beilstein/REAXYS Number:
1723797
Technischer Dienst
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Unterstützung erhaltenQuality Segment
sterility
γ-irradiated
product line
BioXtra
form
powder
packaging
vial of 0.292 g
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white to faint yellow
mp
185 °C (dec.) (lit.)
solubility
H2O: 10 mL/vial, clear to slightly hazy
SMILES string
N[C@@H](CCC(N)=O)C(O)=O
InChI
1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1
InChI key
ZDXPYRJPNDTMRX-VKHMYHEASA-N
Gene Information
rat ... Ggt1(116568)
Application
L-Glutamine has been used as a media supplement:
- for cochlear organotypic culturing
- in Iscove′s modified Dulbecco′s medium for HeLa cells culturing
- in Dulbecco′s modified Eagle′s medium for primary hepatocyte cell culturing
Qualified for use in cell culture applications, especially serum-free cell culture.
Biochem/physiol Actions
Glutamine mediates protein turnover via cellular mTOR (mammalian target of rapamycin) signalling. It is also known to be associated with the inhibition of apoptosis.
Glutaminsäure-Vorläufer und Metabolit; stimulierende Aminosäure
L-glutamine is an essential amino acid that is a crucial component of culture media, and serves as a major energy source for cells in culture. Optimal cell performance usually requires supplementation of the medium with L-glutamine prior to use.
Packaging
50 mL amber serum vial with rubber stopper.
Preparation Note
Prepares a 200 mM solution when reconstituted to 10 mL with sterile water.
Other Notes
The dipeptide L-Ala-LGln is frequently used in modern serum-free media formulations because it provides a more stable form of glutamine in vitro.
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Dieser Artikel | |||
|---|---|---|---|
| description γ-irradiated, BioXtra, suitable for cell culture | description meets USP testing specifications, suitable for cell culture, 99.0-101.0%, from non-animal source | description ReagentPlus®, ≥99% (HPLC) | description certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland |
| form powder | form powder | form powder | form - |
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) - | technique(s) HPLC: suitable, gas chromatography (GC): suitable |
| product line BioXtra | product line - | product line ReagentPlus® | product line TraceCERT® |
| solubility H2O: 10 mL/vial, clear to slightly hazy | solubility H2O: 25 mg/mL | solubility 1 M HCl: 50 mg/mL, clear to slightly hazy, colorless | solubility - |
| color white to faint yellow | color white | color white to off-white | color white |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level 300 |
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Is the molecular weight of L-Glutamine 146.14 or 146.15? The label information changed.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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