F6800

Fenoldopam monohydrobromide

≥98%

• Synonym(e): 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol monohydrobromide, SKF-82526
• Empirische Formel (Hill-System): C₁₆H₁₆ClNO₃ · HBr
• CAS-Nummer: 67287-54-1
• Molekulargewicht: 386.67
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278441
• EC Number: 266-634-7
• MDL number: MFCD27977921

Eigenschaften

• Produktname: Fenoldopam monohydrobromide, ≥98%
• InChI key: DSGOSRLTVBPLCU-UHFFFAOYSA-N
• InChI: 1S/C16H16ClNO3.BrH/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21;/h1-4,7,13,18-21H,5-6,8H2;1H
• SMILES string: ClC1=C(O)C(O)=CC2=C1CCNCC2C3=CC=C(O)C=C3.[H]Br
• assay: ≥98%
• form: solid
• storage condition: protect from light; under inert gas
• color: off-white
• solubility: DMSO: >12 mg/mL; H₂O: 4.75 mg/mL
• storage temp.: 2-8°C
• Gene Information: human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), DRD1(1812)

Beschreibung

Biochem/physiol Actions

Fenoldopam is a selective dopamine agonist that is being considered for the parenteral treatment of systemic hypertension. In both an oral and parenteral form, fenoldopam causes peripheral vasodilation by stimulating dopamine-1 adrenergic receptors. Intravenous fenoldopam may provide advantages over sodium nitroprusside because it can induce both a diuresis and natriuresis, is not light sensitive, and is not associated with cyanide toxicity. There is no evidence for rebound hypertension after discontinuation of fenoldopam infusion.

Features and Benefits

This compound was developed by Hospira. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H317,H319,H334
• pcodes: P261 - P280 - P305 + P351 + P338 - P342 + P311
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Sens. 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves