F1183

FK888 hydrate

• Synonym(e): FK888 hydrate, (4R)-4-Hydroxy-1-[(1-methyl-1H-indol-3-yl)carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-L-alaninamide hydrate, N2-[(4R)-4-hydroxyl-1-(1-methyl-1H-indol-3-yl)carbonyl-L-prolyl]-N-methyl-N-phenylmethyl-3-(2-naphthyl)-L-alaninamide hydrate
• Empirische Formel (Hill-System): C₃₆H₃₆N₄O₄ · xH₂O
• CAS-Nummer: 138449-07-7
• Molekulargewicht: 588.70 (anhydrous basis)
• MDL-Nummer: MFCD19686961
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329799676
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D -135 to -145°, c = 1 in methanol
• Farbe: white to tan
• Löslichkeit: DMSO: ≥13 mg/mL
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• SMILES String: O.CN(Cc1ccccc1)C(=O)[C@H](Cc2ccc3ccccc3c2)NC(=O)[C@@H]4C[C@@H](O)CN4C(=O)c5cc6ccccc6n5C
• InChI: 1S/C36H36N4O4.H2O/c1-38(22-24-10-4-3-5-11-24)35(43)30(19-25-16-17-26-12-6-7-13-27(26)18-25)37-34(42)32-21-29(41)23-40(32)36(44)33-20-28-14-8-9-15-31(28)39(33)2;/h3-18,20,29-30,32,41H,19,21-23H2,1-2H3,(H,37,42);1H2/t29-,30+,32+;/m1./s1
• InChIKey: QOMUXFWVTKDGGK-ZGCLDRINSA-N

Beschreibung

Biochem./physiol. Wirkung

Selective, high affinity tachykinin NK1 receptor antagonist.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable