F0176

Anti-FLI-1 antibody produced in sheep

fractionated antiserum, buffered aqueous solution

• MDL-Nummer: MFCD01864665
• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: sheep
• Konjugat: unconjugated
• Antikörperform: fractionated antiserum
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 52 kDa
• Speziesreaktivität: human, mouse
• Methode(n): western blot: suitable using whole extracts from mouse erythroleukemia cell lines, DP16-1 and CB7 and human T-cell line.
• UniProt-Hinterlegungsnummer: Q01543
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... FLI1(2313) ; mouse ... Fli1(14247)

Beschreibung

Immunogen

GST fusion protein of the N-terminus of Fli-1 corresponding to amino acids 1-239.

Anwendung

Anti-FLI-1 antibody produced in sheep is suitable for western blotting using whole extracts from mouse erythroleukemia cell lines, DP16-1 and CB7 and human T-cell line.

Biochem./physiol. Wirkung

Friend leukemia integration 1 transcription factor (FLI1) is a protein that is encoded by the FLI1 gene in humans and is a member of Ets transcription factor family. It is a proto-oncogene and located on human chromosome 11q23-24. FLI1 may be involved in human sarcomas, leukemias and lymphomas. It may play an important role in the posttranscriptional regulation of the Fli-1 transcript. Alteration in the transcriptional activation function of Fli-1 may be responsible for human malignancies. It is a novel ETS transcription factor involved in gene fusions in prostate cancer.

Physikalische Form

Solution in 0.01 M phosphate buffered saline, containing 0.08% sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.