E4404

Anti-EphA8 antibody produced in goat

affinity isolated antibody, lyophilized powder

• UNSPSC Code: 51111800
• NACRES: NA.41
• MDL number: MFCD04040318
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ELISA (i), WB
• Citations: 2

Eigenschaften

• biological source: goat
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: mouse
• technique(s): indirect ELISA: 0.5-1.0 μg/mL, western blot: 0.1-0.2 μg/mL
• UniProt accession no.: O09127
• storage temp.: −20°C
• Gene Information: mouse ... Epha8(13842)

Beschreibung

General description

The antibody demonstrates ~5% cross-reactivity with recombinant mouse EphA6, EphA7, EphA2, and EphA3 in ELISA and immunoblotting assays. Also, there is approximately 5% cross-reactivity with recombinant human EphA1 and recombinant rat EphA5.

Immunogen

purified recombinant mouse EphA8 extracellular domain.

Biochem/physiol Actions

EPH receptor A8 is a protein-tyrosine kinase family that belongs to the ephrin receptor subfamily. It regulates developmental events, particularly those of the nervous system. EphA8 binds p110γ isoform of PI3-kinase and regulates the integrin-mediated cell adhesion.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)