E114

EHNA hydrochloride

≥98% (HPLC), powder, adenosine deaminase inhibitor

• Synonym(e): erythro-9-(2-Hydroxy-3-nonyl)­adenine hydrochloride, erythro-9-Amino-β-hexyl-­α-methyl-9H-purine-9-ethanol hydrochloride
• Empirische Formel (Hill-System): C₁₄H₂₃N₅O · HCl
• CAS-Nummer: 58337-38-5
• Molekulargewicht: 313.83
• MDL-Nummer: MFCD00151066
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24277713
• NACRES: NA.77

Eigenschaften

• product name: EHNA hydrochloride, ≥98% (HPLC)
• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Lagerbedingungen: desiccated
• Löslichkeit: DMSO: >10 mg/mL; H₂O: >10 mg/mL
• SMILES String: Cl[H].CCCCCC[C@H]([C@H](C)O)n1cnc2c(N)ncnc12
• InChI: 1S/C14H23N5O.ClH/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19;/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17);1H/t10-,11+;/m0./s1
• InChIKey: VVDXNJRUNJMYOZ-VZXYPILPSA-N
• Angaben zum Gen: human ... ADORA1(134) , ADORA2A(135) , ADORA2B(136) , ADORA3(140)

Beschreibung

Allgemeine Beschreibung

EHNA is an adenosine deaminase inhibitor. It possesses antitumor action.

Anwendung

EHNA hydrochloride has been used to treat microexplant culture to examine the direction and the motor responsible for the movement of autophagosomes in axons. It has also been used in nucleoside supplementation to inhibit the breakdown of deoxyadenosine by the enzyme adenosine deaminase.

Biochem./physiol. Wirkung

Adenosine deaminase inhibitor.

Leistungsmerkmale und Vorteile

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)