D4297

Deoxycholsäure

BioXtra, ≥98% (HPLC)

• Synonym(e): 3α,12α-Dihydroxy-5β-cholansäure, 7-Deoxycholsäure, Deoxycholsäure
• Empirische Formel (Hill-System): C₂₄H₄₀O₄
• CAS-Nummer: 83-44-3
• Molekulargewicht: 392.57
• Beilstein: 3219882
• EG-Nummer: 201-478-5
• MDL-Nummer: MFCD00003673
• UNSPSC-Code: 12161900
• PubChem Substanz-ID: 24893857

Eigenschaften

• Biologische Quelle: bovine bile (ex gall bladder)
• Beschreibung: anionic
• Produktlinie: BioXtra
• Assay: ≥98% (HPLC)
• Form: powder
• Mol-Gew.: micellar avg mol wt 1200-5000
• Aggregatnummer: 3-12
• Verunreinigungen: ≤0.005% Phosphorus (P); ≤0.1% Insoluble matter
• Glührückstand: ≤0.1%
• CMC: 2-6
• mp (Schmelzpunkt): 171-174 °C (lit.)
• Kationenspuren: Al: ≤0.001%; Ca: ≤0.01%; Cu: ≤0.0005%; Fe: ≤0.005%; K: ≤0.005%; Mg: ≤0.005%; NH₄⁺: ≤0.05%; Na: ≤0.02%; Pb: ≤0.001%; Zn: ≤0.0005%
• HLB: 16
• Funktionelle Gruppe: carboxylic acid
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
• InChI: 1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1
• InChIKey: KXGVEGMKQFWNSR-LLQZFEROSA-N
• Angaben zum Gen: human ... ATIC(471)

Beschreibung

Allgemeine Beschreibung

Deoxycholic acid is a bile acid that may affect intracellular signaling and gene expression.

Anwendung

Deoxycholic acid has been used in a study to assess how physiological concentrations of ursodeoxycholic acid (UDCA) vs. deoxycholic acid (DCA) affect barrier function in mouse intestinal tissue. It has also been used in a study to characterize bile formation in a mouse model with hepatic disruption of the cytochrome p450 (CYP) oxidoreductase gene.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302,H315,H319,H335
• P-Sätze: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves