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C7214

Sigma-Aldrich

Monoclonal Anti-Cyclin D3 antibody produced in mouse

clone DCS-22, ascites fluid

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About This Item

MDL-Nummer:
MFCD00239666
UNSPSC-Code:
12352203

Biologische Quelle

mouse

Konjugat

unconjugated

Antikörperform

ascites fluid

Klon

DCS-22, monoclonal

Mol-Gew.

antigen 31-34 kDa

Enthält

15 mM sodium azide

Speziesreaktivität

canine, human, rat, monkey, mouse

Methode(n)

immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable
indirect ELISA: suitable
microarray: suitable
western blot: 1:4,000 using a rat osteosarcoma cell line (ROS) extract

Isotyp

IgG1

Versandbedingung

dry ice

Lagertemp.

−20°C

Angaben zum Gen

human ... CCND3(896)
mouse ... Ccnd3(12445)
rat ... Ccnd3(25193)

Spezifität

It does not cross-react with other D-type cyclins.

Immunogen

recombinant human cyclin D3 protein.

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Stacey A Leisenfelder et al.
Journal of virology, 80(11), 5577-5587 (2006-05-16)
In its course of human infection, varicella-zoster virus (VZV) infects rarely dividing cells such as dermal fibroblasts, differentiated keratinocytes, mature T cells, and neurons, none of which are actively synthesizing DNA; however, VZV is able to productively infect them and
J Bartkova et al.
International journal of cancer, 65(3), 323-327 (1996-01-26)
The D-type cyclins are positive regulators of the G1 phase of the mammalian cell cycle. Cyclins D1 or D2 are over-expressed in several types of cancer, transform rodent cells in culture and therefore harbor hallmarks of cellular proto-oncogenes. In contrast
Daxiang Cui et al.
Toxicology letters, 155(1), 73-85 (2004-12-09)
The influence of single-walled carbon nanotubes (SWCNTs) on human HEK293 cells is investigated with the aim of exploring SWCNTs biocompatibility. Results showed that SWCNTs can inhibit HEK293 cell proliferation, decrease cell adhesive ability in a dose- and time-dependent manner. HEK293
Sandra Herrero-González et al.
Glia, 57(2), 222-233 (2008-08-30)
In previous studies, we showed that endothelin-1 increased astrocyte proliferation and glucose uptake. These effects were similar to those observed with other gap junction inhibitors, such as carbenoxolone (CBX). Because 24-h treatment with endothelin-1 or CBX downregulates the expression of
Mary Tsikitis et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(34), 12129-12134 (2005-08-16)
Rhabdoid tumors are aggressive pediatric malignancies for which, currently, there are no effective or standard treatment strategies. Rhabdoid tumors arise because of the loss of the tumor suppressor gene INI1. We have previously demonstrated that INI1 represses Cyclin D1 transcription
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