C5499
Cytochrome c Oxidase from bovine heart
5 mg protein/mL
Synonym(e):
EC 1.9.3.1, Ferrocytochrome-c:oxygen oxidoreductase, Complex IV
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Über diesen Artikel
CAS-Nummer:
UNSPSC Code:
12352204
NACRES:
NA.32
EC Number:
232-586-0
MDL number:
Specific activity:
≥20 units/mg protein
Biological source:
bovine heart
Concentration:
5 mg protein/mL
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Unterstützung erhaltenbiological source
bovine heart
Quality Level
form
buffered aqueous solution
specific activity
≥20 units/mg protein
mol wt
300-350 kDa by gel filtration
greener alternative product characteristics
Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
concentration
5 mg protein/mL
greener alternative category
, Enabling
shipped in
dry ice
storage temp.
−20°C
Verwandte Kategorien
1 of 4
Dieser Artikel | |||
|---|---|---|---|
| specific activity ≥20 units/mg protein | specific activity ≥200 units/mg protein | specific activity ≥200 U/mg | specific activity - |
| biological source bovine heart | biological source - | biological source bacterial (Pseudomonas spp.) | biological source bovine heart |
| form buffered aqueous solution | form lyophilized powder | form powder | form powder |
| concentration 5 mg protein/mL | concentration - | concentration - | concentration - |
| shipped in dry ice | shipped in - | shipped in - | shipped in - |
| mol wt 300-350 kDa by gel filtration | mol wt 23-27 kDa by SDS-PAGE | mol wt - | mol wt 12327 Da |
General description
Research area: Cell cycle
Cytochrome c oxidase contains 13 subunits, encoded by mitochondrial genes and nuclear genome. It is comprised of two heme groups (Fea and Fea3) and two copper centers, CuA and CuB.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for energy efficiency and waste prevention when used in biofuel cell research. For more information see the article in biofiles.
Cytochrome c oxidase contains 13 subunits, encoded by mitochondrial genes and nuclear genome. It is comprised of two heme groups (Fea and Fea3) and two copper centers, CuA and CuB.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for energy efficiency and waste prevention when used in biofuel cell research. For more information see the article in biofiles.
Application
Cytochrome c Oxidase (CcO) from bovine heart has been used:
Biochem/physiol Actions
Cytochrome c oxidase is the principal terminal oxidase of high oxygen affinity in the aerobic metabolism of all animals, plants, yeasts and some bacteria.
Cytochrome c oxidase is the principal terminal oxidase of high oxygen affinity in the aerobic metabolism of all animals, plants, yeasts and some bacteria. It is present in the mitochondria of the more highly developed cells and in the cytoplasmic membrane of bacteria. Cytochrome c oxidase catalyses the electron transfer from cytochrome c to O2. This electron-transfer process produces a proton gradient across the membrane, which in turn drives the production of ATP. This enzyme is unique in providing energy for the cell bycoupling the electron transport through the cytochrome chain with the process of oxidative phosphorylation.
Physical form
Supplied as a solution in 25 mM Tris-HCl buffer, pH 7.8, 5 mM EDTA, and 39 mM n-dodecyl β·-D-maltoside.
Other Notes
One unit of cytochrome c oxidase will oxidize 1.0 μmole of ferrocytochrome c per min. at 25 °C at pH 6.0.
Lagerklasse
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Reply to Giamogante et al.: The effect of low cyanide on O2 consumption is best observed in physiological, rather than reductionist, systems.
Karim Zuhra et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(39) (2021-09-22)
Cytochrome c Oxidase Dysfunction in Oxidative Stress
Srinivasan S & Avadhani NG
Free Radical Biology & Medicine (2013)
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Claudia R Oliva et al.
The Journal of biological chemistry, 291(46), 24188-24199 (2016-09-30)
The enzyme cytochrome c oxidase (CcO) or complex IV (EC 1.9.3.1) is a large transmembrane protein complex that serves as the last enzyme in the respiratory electron transport chain of eukaryotic mitochondria. CcO promotes the switch from glycolytic to oxidative
Verwandter Inhalt
Instructions
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C5499-250UG | 04061833502235 |
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