Alle Fotos(1)

Wichtige Dokumente

Ursprungszeugnis (CoO)/Analysenzertifikate (CoA)

Gesamtdokumentation anzeigen

C4147

γ-Carboxy-L-glutaminsäure

Name: γ-Carboxy-<SC>L</SC>-glutaminsäure
Brand: SIGMA

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise

Alle Fotos(1)

About This Item

Empirische Formel (Hill-System):

C₆H₉NO₆

CAS-Nummer:

53861-57-7

Molekulargewicht:

191.14

Beilstein:

2417114

EG-Nummer:

258-825-9

MDL-Nummer:

MFCD00011673

UNSPSC-Code:

12352200

PubChem Substanz-ID:

24892669

Lagertemp.

−20°C

SMILES String

N[C@@H](CC(C(O)=O)C(O)=O)C(O)=O

InChI

1S/C6H9NO6/c7-3(6(12)13)1-2(4(8)9)5(10)11/h2-3H,1,7H2,(H,8,9)(H,10,11)(H,12,13)/t3-/m0/s1

InChIKey

UHBYWPGGCSDKFX-VKHMYHEASA-N

Angaben zum Gen

rat ... Grm2(24415)

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Biochem./physiol. Wirkung

Gamma-carboxy-L-glutamic acid (GLA) is used as a metabotropic glutamate receptor (mGluR) subtype ligand wherein GLA is a group-II mGlu2 receptor and group-III mGlu7, mGlu8 antagonist and group-III mGlu4, mGlu6 agonist.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Therapeutic potential of group III metabotropic glutamate receptors.

Hilde Lavreysen et al.

Current medicinal chemistry, 15(7), 671-684 (2008-03-14)

Metabotropic glutamate (mGlu) receptors have received much attention, driven by a strong belief in the potential of these modulatory glutamate receptors as drug targets. So far, major drug discovery programs have largely focused on group I (mGlu1 and 5) and

Glutamate metabotropic receptors as targets for drug therapy in epilepsy.

Randal X Moldrich et al.

European journal of pharmacology, 476(1-2), 3-16 (2003-09-13)

Metabotropic glutamate (mGlu) receptors have multiple actions on neuronal excitability through G-protein-linked modifications of enzymes and ion channels. They act presynaptically to modify glutamatergic and gamma-aminobutyric acid (GABA)-ergic transmission and can contribute to long-term changes in synaptic function. The recent

Comparative effect of L-CCG-I, DCG-IV and gamma-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes.

I Brabet et al.

Neuropharmacology, 37(8), 1043-1051 (1998-12-02)

In a previous study we reported that the addition of a carboxylic group to the mGlu receptor agonist aminocyclopentane-1,3-dicarboxylate (ACPD) changes its properties from agonist to antagonist at both mGlu1 and mGlu2 receptors, and resulted in an increase in affinity

Group II and group III metabotropic glutamate receptor agonists depress synaptic transmission in the rat spinal cord dorsal horn.

G Gerber et al.

Neuroscience, 100(2), 393-406 (2000-09-29)

The effects of group II and group III metabotropic glutamate receptor agonists on synaptic responses evoked by primary afferent stimulation in the dorsal horn, but mostly substantia gelatinosa, neurons were studied in the spinal cord slice preparation using conventional intracellular

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.