C3242

CDKi hydrochloride

≥98% (HPLC), solid

• Synonym(e): 2,4-Diamino-5-oxo-pyrimidine hydrochloride
• Empirische Formel (Hill-System): C₄H₆N₄O · xHCl
• CAS-Nummer: 70035-83-5
• Molekulargewicht: 126.12 (free base basis)
• MDL-Nummer: MFCD08277042
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24724437

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: solid
• Löslichkeit: H₂O: 21 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: Cl[H].Nc1ncc(O)c(N)n1
• InChI: 1S/C4H6N4O.ClH/c5-3-2(9)1-7-4(6)8-3;/h1,9H,(H4,5,6,7,8);1H
• InChIKey: KEFSYBXFZWLDQU-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

CDKi hydrochloride is a potent and selective ATP competitiive inhibitor of cycB-CDK1, cycE-CDK2, and cycD1-CDK4. Demonstrates significant inhibitory activity against a variety of tumor type both in vitro and in vivo.

Leistungsmerkmale und Vorteile

This compound is featured on the CDKs page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves