B170
BW373U86 hydrochloride
powder
Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)
About This Item
Empirische Formel (Hill-System):
C27H37N3O2 · HCl
CAS-Nummer:
Molekulargewicht:
472.06
MDL-Nummer:
UNSPSC-Code:
41116107
Form
powder
Methode(n)
HPLC: suitable
gas chromatography (GC): suitable
Farbe
tan
Löslichkeit
H2O: 4 mg/mL
Format
neat
Anwendung
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem./physiol. Wirkung
Potent, nonpeptide δ-opioid receptor agonist.
Vorsicht
Hygroscopic, store desiccated
Rechtliche Hinweise
Sold with the permission of Delta Pharmaceuticals Inc
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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Ai Hashimoto et al.
Toxicologic pathology, 48(3), 509-523 (2020-01-04)
Macrophages and myofibroblasts are important in fibrogenesis. The cellular characteristics in pancreatic fibrosis remain to be investigated. Pancreatic fibrosis was induced in F344 rats by a single intravenous injection of dibutyltin dichloride. Histopathologically, the induced pancreatic fibrosis was divided into
K J Chang et al.
The Journal of pharmacology and experimental therapeutics, 267(2), 852-857 (1993-11-01)
Four different opioid receptor binding assays and three different isolated tissue studies were used to screen for delta receptor-selective nonpeptidic compounds. (+/-)-4-((alpha-R*)-alpha-((2S*,5R*)-4-Allyl-2,5- dimethyl-1-piperazinyl)-3-hydroxybenzyl)-N,N-diethylbenzamide (BW373U86) was a potent delta receptor-selective ligand in receptor binding assays. The Ki values were 1.8 +/-
S D Comer et al.
The Journal of pharmacology and experimental therapeutics, 267(2), 866-874 (1993-11-01)
Several opioid agonists were evaluated in pigeons trained to discriminate i.m. injections of sterile water from either the mu agonist morphine (5.6 mg/kg), the kappa agonist bremazocine (0.032mg/kg) or (+/-)-4-((alpha-R*)-alpha-((2S*,5R*)-4-allyl-2,5-dimethyl-1- piperazinyl)-3-hydroxybenzyl)-N,N-diethylbenzamide (BW373U86; 0.56 mg/kg). Pigeons were trained to peak one
S R Childers et al.
Molecular pharmacology, 44(4), 827-834 (1993-10-01)
BW373U86 is a potent and highly selective nonpeptidic agonist for delta-opioid receptors. To determine its ability to couple with G protein-linked second messenger systems, this study examined the effects of BW373U86 on the inhibition of adenylyl cyclase and the stimulation
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