A9451

Aristolochiasäure I Natriumsalz

powder, ≥97%

• Synonym(e): Aristolochic acid sodium salt
• Empirische Formel (Hill-System): C₁₇H₁₀NNaO₇
• CAS-Nummer: 10190-99-5
• Molekulargewicht: 363.25
• NACRES: NA.77
• PubChem Substance ID: 24891454
• UNSPSC Code: 12352202
• EC Number: 233-463-4
• MDL number: MFCD00210760
• Assay: ≥97%
• Form: powder
• Solubility: H₂O: 50 mg/mL

Eigenschaften

• Quality Segment: 200
• assay: ≥97%
• form: powder
• solubility: H₂O: 50 mg/mL
• SMILES string: [Na+].COc1cccc2c1cc([N+]([O-])=O)c3c(cc4OCOc4c23)C([O-])=O
• InChI: 1S/C17H11NO7.Na/c1-23-12-4-2-3-8-9(12)5-11(18(21)22)14-10(17(19)20)6-13-16(15(8)14)25-7-24-13;/h2-6H,7H2,1H3,(H,19,20);/q;+1/p-1
• InChI key: BQVOPWJSBBMGBR-UHFFFAOYSA-M

Beschreibung

Biochem/physiol Actions

Component of some Chinese herbal medicines, and responsible for their nephrotoxicity. Prodrug activated by reduction of the nitro group to an amine, which forms cytotoxic DNA adducts.

Sicherheitshinweise

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301 + H311 + H331,H351
• pcodes: P202 - P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 2
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges