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A273

Sigma-Aldrich

Monoclonal Anti-Na+/K+ ATPase (α3 Subunit) antibody produced in mouse

1 mg/mL, clone XVIF9-G10, ascites fluid

Synonym(e):

Anti-AHC2, Anti-ATP1A1, Anti-CAPOS, Anti-DEE99, Anti-DYT12, Anti-RDP

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About This Item

MDL-Nummer:
MFCD01322380
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

200

Konjugat

unconjugated

Antikörperform

ascites fluid

Antikörper-Produkttyp

primary antibodies

Klon

XVIF9-G10, monoclonal

Mol-Gew.

antigen ~110 kDa

Speziesreaktivität

human, rat, monkey, sheep, rabbit, guinea pig, canine

Konzentration

1 mg/mL

Methode(n)

immunohistochemistry (frozen sections): 3 μg
western blot: 1 μg

Isotyp

IgG1

UniProt-Hinterlegungsnummer

P13637

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ATP1A3(478)
rat ... Atp1a3(24213)

Allgemeine Beschreibung

Mouse monoclonal anti-Na+/K+ ATPase (α3 subunit) antibody reacts specifically with Na+/K+ ATPase α3 subunit. By immunoblotting, the product reacts with human, monkey, sheep, canine, rabbit, guinea pig and rat tissues in which the α3 subunit is expressed. Immunohistochemical staining is consistent with the plasma membrane localization of Na+/K+ ATPase.
Na+/K+ transporting ATPase subunit α1 is an ion transport pump critical for maintaining the gradient of Na and K ions across the plasma membrane.

Immunogen

canine cardiac microsomes.

Anwendung

Mouse monoclonal anti-Na+/K+ ATPase (α3 subunit) antibody has been used for chemiluminescent western blot analysis. The product has also been used for co-immunoprecipitation applications.

Physikalische Form

Solution in phosphate buffered saline containing 0.05% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Athina Zouzoulas et al.
The Journal of biological chemistry, 281(13), 8539-8544 (2006-02-01)
The gamma modulator (FXYD 2) is a member of the FXYD family of single transmembrane proteins that modulate the kinetic behavior of Na,K-ATPase. This study concerns the identification of regions in the alpha subunit that are important for its functional
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