A123

R-(+)-p-Aminoglutethimide (+)-tartrate salt

• Empirische Formel (Hill-System): C₁₃H₁₆N₂O₂ · C₄H₆O₆
• CAS-Nummer: 57344-88-4
• Molekulargewicht: 382.37
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 24890514

Eigenschaften

• Assay: 99.4% (HPLC)
• mp (Schmelzpunkt): 124-127 °C
• Versandbedingung: ambient
• SMILES String: O[C@H]([C@@H](O)C(O)=O)C(O)=O.CC[C@@]1(CCC(=O)NC1=O)c2ccc(N)cc2
• InChI: 1S/C13H16N2O2.C4H6O6/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9;5-1(3(7)8)2(6)4(9)10/h3-6H,2,7-8,14H2,1H3,(H,15,16,17);1-2,5-6H,(H,7,8)(H,9,10)/t13-;1-,2-/m11/s1
• InChIKey: DQUXPVVSVXIQNE-IMXLTCNTSA-N

Beschreibung

Biochem./physiol. Wirkung

Inhibitor of aromatases involved in conversion of androgens to estrogens, and thus useful in chemotherapy of hormone-sensitive tumors (e.g., breast cancer). Also inhibits corticosteroid biosynthesis, termed a "medical adrenalectomy."

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)