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Merck

78973

Kolliphor P 188 Micro

Synonym(e):

Poly-(ethylenglykol)-block-poly-(propylenglykol)-block-poly-(ethylenglykol), Lμtrol micro 68, Poloxamer 188, mikronisiert

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Über diesen Artikel

CAS-Nummer:
9003-11-6
UNSPSC Code:
12161900
NACRES:
NA.25
MDL number:
MFCD00082049

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Unterstützung erhalten

SMILES string

O2C(C2)C.O1CC1

InChI

1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2

InChI key

RVGRUAULSDPKGF-UHFFFAOYSA-N

form

powder

mol wt

~7680-9510 g/mol

composition

oxyethylene content, 79.9-83.7%

technique(s)

DNA extraction: suitable, DNA purification: suitable, NMR: suitable, RNA extraction: suitable, RNA purification: suitable

impurities

organic volatile impurities, complies (meets USP requirements), ≤0.4% total ash, ≤0.75% water, ≤1 ppm ethylene oxide, ≤20 ppm heavy metals, ≤5 ppm 1,4-dioxane, ≤5 ppm propylene oxide, 50-125 ppm butylhydroxytoluene

color

APHA: ≤100

particle size distribution

, coeff var ≤10% (residue, No. 140 USS), , coeff var ≤50% (residue, No 270 USS)

pH

5.0-7.5 (2.5% in H2O)

suitability

complies for Infrared spectrum

Quality Level

100

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Dieser Artikel
1.3711215759K4894
Poloxamer 188, micronized

Sigma-Aldrich

78973

Poloxamer 188, micronized

Poloxamer 188 EMPROVE® EXPERT, (stabilized with 70ppm BHT), Ph. Eur., ChP, NF

SAFC

1.37112

Poloxamer 188

Poloxamer 188

Sigma-Aldrich

15759

Poloxamer 188

Poloxamer 188 solid

Sigma-Aldrich

K4894

Poloxamer 188

technique(s)

DNA extraction: suitable, NMR: suitable, RNA purification: suitable, DNA purification: suitable, RNA extraction: suitable

technique(s)

API processing | nano-milling: suitable

technique(s)

-

technique(s)

-

suitability

complies for Infrared spectrum

suitability

-

suitability

-

suitability

-

form

powder

form

solid

form

solid

form

solid

impurities

organic volatile impurities, complies (meets USP requirements), ≤0.75% water, ≤20 ppm heavy metals, ≤5 ppm propylene oxide, ≤0.4% total ash, ≤5 ppm 1,4-dioxane, ≤1 ppm ethylene oxide, 50-125 ppm butylhydroxytoluene

impurities

-

impurities

≤0.25% ethylene glycol and diethylene glycol, ≤0.4% total ash, ≤1 ppm ethylene oxide, ≤1.0% water, ≤2 ppm arsenic traces, ≤20 ppm heavy metals, ≤5 ppm dioxan, ≤5 ppm propylene oxide, 50-150 ppm butylhydroxytoluene

impurities

-

Quality Level

100

Quality Level

500

Quality Level

200

Quality Level

300

mol wt

~7680-9510 g/mol

mol wt

-

mol wt

~7680-9510 g/mol

mol wt

8.400 g/mol

Other Notes

The Poloxamer 188 grades are poloxamers from the extensive line of Pluronic® block copolymers.
average molecular weight/mass 7680-9510 g/mol

Legal Information

Pluronic is a registered trademark of BASF

Lagerklasse

11 - Combustible Solids

wgk

WGK 1

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
BCCK1944
BCCF6791
BCCB9442
BCBW8463
BCBT6082

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Die Dokumentenbibliothek aufrufen

Houjian Gong et al.
Langmuir : the ACS journal of surfaces and colloids, 28(38), 13590-13600 (2012-09-08)
The block polyethers PEO-PPO-ph-PPO-PEO (BPE) and PPO-PEO-ph-PEO-PPO (BEP) are synthesized by anionic polymerization using bisphenol A as initiator. Compared with Pluronic P123, the aggregation behaviors of BPE and BEP at an air/water interface are investigated by the surface tension and
Xijun Zhang et al.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 31(6), 842-845 (2011-12-17)
This study examined the effect of P85 (a pluronic block copolymer) and microbubble (MB) ultrasound contrast agents under ultrasound irradiation on gene transfection and expression. The pEGFP plasmids that can encode enhanced green fluorescent protein (pEGFP) served as a report
Mi Mi Wan et al.
Journal of colloid and interface science, 377(1), 497-503 (2012-04-18)
New concept on the promotion of immobilization and catalytic activity of enzyme on mesoporous silica through template micelles is proposed and realized in this paper. Proper P123 templates are controllable retained in the as-synthesized SBA-15, not only to anchor the
Laurien Buitinga et al.
Clinical and experimental rheumatology, 29(5), 783-789 (2011-10-04)
The Time Trade-Off (TTO) is an instrument used for valuing health-related quality of life. This study evaluated the test-retest reliability of a computer TTO in rheumatoid arthritis (RA), and compared the computer with the interview TTO regarding feasibility and agreement.
Tsz Chung Lai et al.
Colloids and surfaces. B, Biointerfaces, 99, 27-37 (2011-10-18)
Polyplex particles formed with plasmid DNA (pDNA) and Pluronic P85-block-poly{N-[N-(2-aminoethyl)-2-aminoethyl]aspartamide} (P85-b-P[Asp(DET)]) demonstrated highly effective transfection ability compared to PEG-based block cationomer, PEG-b-P[Asp(DET)]. Ternary polyplexes comprising PEG-b-P[Asp(DET)], poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide)-b-P[Asp(DET)] (P(EPE)-b-P[Asp(DET)]) used as an analog of P85-b-P[Asp(DET)], and pDNA were
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