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Merck

74593

Supelco

Obidoximchlorid

analytical standard

Synonym(e):

1,1′-(Oxydimethylen)-bis-(pyridinium-4-carbaldoxim)-dichlorid, Bis-(4-formylpyridiniomethyl)-ether-dioxim, Toxogonin

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About This Item

Empirische Formel (Hill-System):
C14H16Cl2N4O3
CAS-Nummer:
Molekulargewicht:
359.21
Beilstein:
4117377
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Assay

≥97.0% (HPLC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Verunreinigungen

≤1.0% water (calculated from elemental analysis)

Format

neat

SMILES String

[Cl-].[Cl-].O\N=C\c1cc[n+](COC[n+]2ccc(cc2)\C=N\O)cc1

InChI

1S/C14H14N4O3.2ClH/c19-15-9-13-1-5-17(6-2-13)11-21-12-18-7-3-14(4-8-18)10-16-20;;/h1-10H,11-12H2;2*1H

InChIKey

ZIFJVJZWVSPZLE-UHFFFAOYSA-N

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Allgemeine Beschreibung

Obidoxime chloride is a drug, belonging to the group of oximes. It is found to be useful for the treatment of organophosphorus (OP) poisoning, since it has the ability to reverse the binding of organophosphorus compounds to the enzyme acetylcholinesterase (AChE).

Anwendung

Obidoxime chloride may be used as a reference standard for the determination of obidoxime in a parenteral injection device using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Antidote for organophosphate nerve agent poisoning

Empfohlene Produkte

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

Lot/Batch Number

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Handbook of Pesticide Toxicology, Two-Volume Set: Principles and Agents, Volume 1, 1(2) (2001)
Best Synthetic Methods: Organophosphorus (V) Chemistry (2014)
Handbook of Toxicology of Chemical Warfare Agents (2015)
Simple high-performance liquid chromatographic method for determination of atropine and obidoxime in a parenteral injection device.
Journal of Chromatography A, 1057(1-2), 237-239 (2004)
Dietrich E Lorke et al.
Journal of applied toxicology : JAT, 39(11), 1506-1515 (2019-07-03)
Organophosphates, useful agents as pesticides, also represent a serious danger due to their high acute toxicity. There is indication that oximes, when administered before organophosphate exposure, can protect from these toxic effects. We have tested at equitoxic dosage (25% of

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